"The beautiful wood staircase to the upstairs rooms showed amazing craftsmanship."
Rachel from United States
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"Incredibly restored, classy & tasteful touches and the pics online are authentic to how in looks in real time."
Ken L from United States
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"The bedding and linens are perfection."
Mandy M from United States
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"Beautiful Amish made furniture throughout."
CordeliaMinnesota from United States
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"Beautiful restoration, close proximity to Main Street (and in a lovely neighborhood), thoughtful hosts (and an AMAZING breakfast)."
lynette j from United States
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Restored Fraternity House Boutique Inn in Vermillion, SD
Historic Renovation & Handcrafted Furnishings
Main Street Inn is a restored former University of South Dakota fraternity house. The renovation preserved the original character while adding handcrafted Amish furniture throughout. Local artisans created the woodwork and furnishings, including the staircase and mission-style decor.
Accommodations
The inn offers 5 guest rooms, each with air conditioning and city views. Family rooms are available for larger groups, with spacious layouts and private bathrooms featuring walk-in showers. All rooms include flat-screen TVs with streaming services.
Amenities & Services
The inn serves a complimentary breakfast each morning in the common dining area. Free private parking is available on-site without reservation. Guests have access to a community lounge with a game cabinet and complimentary snacks and drinks on each floor.
Location & Nearby Attractions
Main Street Inn is located within a 7-minute walk of the National Music Museum. The property is close to downtown Vermillion's restaurants and shops. Sioux Gateway Airport is 82 km away, and Union County State Park is 28 km from the inn.
Family-Friendly Accommodations
The inn provides family rooms specifically designed for larger groups, accommodating up to 5 rooms for a full-family booking. The basement offers a separate area for children to gather. Guests have praised the hotel's cleanliness and comfort, making it suitable for families.
Highlights
Renovation: Restored fraternity house with handcrafted Amish furniture
Rooms: 5 guest rooms with family-sized options and streaming services
Dining: Complimentary hot breakfast served daily
Parking: Free on-site private parking without reservation
Location: 7-minute walk to National Music Museum
Family: Family rooms and basement children's area
“This historic fraternity house has been masterfully reborn as a refined inn, where thoughtful restoration meets modern comfort. Its proximity to downtown Vermillion is undeniable, yet the atmosphere remains tranquil, enhanced by truly exceptional breakfasts and the warm attentiveness of its host. It's a place that clearly prioritizes genuine hospitality.”
James DavidEditor-in-Chief at Ussouthdakota
Select your room type
Main Street Inn offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Single Room Bathroom
2 persons
325 sq. feet
1 King-size bed
Air conditioning
Heating
room details
Single Room
2 persons
325 sq. feet
1 King-size bed
Air conditioning
Heating
room details
Deluxe Single Room
2 persons
400 sq. feet
1 King-size bed
Air conditioning
Heating
room details
Show all rooms
Price and Room Availability Calendar
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Facilities
Main Street Inn offers amenities for your comfortable stay and unforgettable experiences
Facilities: Perfect
9.6/10Review score
General
No smoking on site
Wi-Fi
Parking
No pets allowed
Children
Cots
Room features
Air conditioning
Heating
Tea and coffee facilities
Bathroom
Free toiletries
Media
Flat-screen TV
AM/FM alarm clock
Room decor
Carpeted floor
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Main Street Inn Location
221 East Main Street, Vermillion, SD 57069,
Map view
City landmarks
Museum
National Music Museum
2100 ft
Museum
W H Over Museum
1.0 mi
Landmark
Spirit Mound
2.2 mi
Nearby
414 E Clark St The University of South Dakota
Shrine to Music Museum
1800 ft
Restaurants
Leo's Sports Bar and Grill
1500 ft
11 Market St
Explore Vermillion
Explore Vermillion
Top Attractions
Activities
Dining
Entertainment
National Music Museum
8 minutes' walk
World-class collection of musical instruments showcasing global heritage and unique exhibits. Free admission days available.
W H Over Museum
5-minute drive
Local history museum featuring exhibitions on the area's cultural past and diverse artifacts. Ideal for a quick educational visit.
Spirit Mound
6-minute drive
Historic site with scenic trails leading to a striking viewpoint, rich with Native American history and lore.
Shrine to Music Museum
7 minutes' walk
A hidden gem celebrating the legacy of music with a special focus on regional musicians and themes.
Paddleboarding
6-minute drive
Access to paddleboarding at local lakes, offering rentals during summer. Perfect for thrill-seekers looking for water adventure.
Yoga Classes
10 minutes' walk
Local studio offers relaxing yoga sessions. Great for unwinding after a busy day, with classes suitable for all levels.
Leo's Sports Bar and Grill
6 minutes' walk
Casual spot with a lively atmosphere, serving classic American dishes including burgers and wings. Popular for game day.
Local Bar Scene
5-minute drive
Various spots offer live music and trivia nights, catering to nightlife enthusiasts and families. Check local listings for events.
Getting around
City Centre
Vermillion 3 min · 700 ft
Airports
Sioux Gateway (SUX) 110 min · 45.4 mi
Stronsay (soy) 153 min · 63.1 mi
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Property information and rules
Check-in
from 15:00-21:00
Check-out
from 08:00-11:00
Internet
Wireless internet is available in the entire hotel for free.
Pets
Pets are not allowed.
Reviews and Ratings
Feedback about Main Street Inn from previous guests about their experience.
Breakfast
10.0/10
Cleanliness
9.7/10
Comfort
9.7/10
Facilities
9.6/10
Free Wi-Fi
10.0/10
Location
9.6/10
Staff
9.8/10
Value for money
9.7/10
Guest reviews
based on 24 reviews
9.7/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.