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Main Street Inn Vermillion Exterior photoMain Street Inn Vermillion Exterior photoMain Street Inn Vermillion Interior photo

MAIN STREET INN

•
9.7|Perfect
Check rooms and rates
From$197 /nightOnly on Our Website-10%
Check-in
23Oct
Check-out
24Oct
Guests
2 Guests
Key details

About the Hotel

221 East Main Street, Vermillion, SD 57069
-
Close to the National Music Museum
Perfect
9.7
/10
5.0
/5

Restored Fraternity House Boutique Inn in Vermillion, SD

Historic Renovation & Handcrafted Furnishings

Main Street Inn is a restored former University of South Dakota fraternity house. The renovation preserved the original character while adding handcrafted Amish furniture throughout. Local artisans created the woodwork and furnishings, including the staircase and mission-style decor.

Accommodations

The inn offers 5 guest rooms, each with air conditioning and city views. Family rooms are available for larger groups, with spacious layouts and private bathrooms featuring walk-in showers. All rooms include flat-screen TVs with streaming services.

Amenities & Services

The inn serves a complimentary breakfast each morning in the common dining area. Free private parking is available on-site without reservation. Guests have access to a community lounge with a game cabinet and complimentary snacks and drinks on each floor.

Location & Nearby Attractions

Main Street Inn is located within a 7-minute walk of the National Music Museum. The property is close to downtown Vermillion's restaurants and shops. Sioux Gateway Airport is 82 km away, and Union County State Park is 28 km from the inn.

Family-Friendly Accommodations

The inn provides family rooms specifically designed for larger groups, accommodating up to 5 rooms for a full-family booking. The basement offers a separate area for children to gather. Guests have praised the hotel's cleanliness and comfort, making it suitable for families.

Highlights

Renovation: Restored fraternity house with handcrafted Amish furniture

Rooms: 5 guest rooms with family-sized options and streaming services

Dining: Complimentary hot breakfast served daily

Parking: Free on-site private parking without reservation

Location: 7-minute walk to National Music Museum

Family: Family rooms and basement children's area

“This historic fraternity house has been masterfully reborn as a refined inn, where thoughtful restoration meets modern comfort. Its proximity to downtown Vermillion is undeniable, yet the atmosphere remains tranquil, enhanced by truly exceptional breakfasts and the warm attentiveness of its host. It's a place that clearly prioritizes genuine hospitality.”
Hotel logo
James DavidEditor-in-Chief at Ussouthdakota

Select your room type

Main Street Inn offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
  • Single Room Bathroom
    2 persons
    325 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Single Room
    2 persons
    325 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Deluxe Single Room
    2 persons
    400 sq. feet
    1 King-size bed
    Air conditioning
    Heating
Show all rooms

Price and Room Availability Calendar

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Facilities

Main Street Inn offers amenities for your comfortable stay and unforgettable experiences
Facilities: Perfect
9.6/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • No pets allowed

Children

  • Cots

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
Show more

Main Street Inn Location

221 East Main Street, Vermillion, SD 57069
Map view
Nearby
414 E Clark St The University of South Dakota
Shrine to Music Museum
1800 ft
Restaurants
Leo's Sports Bar and Grill
1500 ft
11 Market St
Explore Vermillion
Explore Vermillion
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
National Music Museum
8 minutes' walk
World-class collection of musical instruments showcasing global heritage and unique exhibits. Free admission days available.
W H Over Museum
5-minute drive
Local history museum featuring exhibitions on the area's cultural past and diverse artifacts. Ideal for a quick educational visit.
Spirit Mound
6-minute drive
Historic site with scenic trails leading to a striking viewpoint, rich with Native American history and lore.
Shrine to Music Museum
7 minutes' walk
A hidden gem celebrating the legacy of music with a special focus on regional musicians and themes.
Paddleboarding
6-minute drive
Access to paddleboarding at local lakes, offering rentals during summer. Perfect for thrill-seekers looking for water adventure.
Yoga Classes
10 minutes' walk
Local studio offers relaxing yoga sessions. Great for unwinding after a busy day, with classes suitable for all levels.
Leo's Sports Bar and Grill
6 minutes' walk
Casual spot with a lively atmosphere, serving classic American dishes including burgers and wings. Popular for game day.
Local Bar Scene
5-minute drive
Various spots offer live music and trivia nights, catering to nightlife enthusiasts and families. Check local listings for events.
Getting around
  • City Centre
    Vermillion 3 min  ·  700 ft
  • Airports
    Sioux Gateway (SUX) 110 min  ·  45.4 mi
    Stronsay (soy) 153 min  ·  63.1 mi
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Property information and rules
Check-in
from 15:00-21:00
Check-out
from 08:00-11:00
Internet
Wireless internet is available in the entire hotel for free.
Pets
Pets are not allowed.

Reviews and Ratings

Feedback about Main Street Inn from previous guests about their experience.
Breakfast
10.0/10
Cleanliness
9.7/10
Comfort
9.7/10
Facilities
9.6/10
Free Wi-Fi
10.0/10
Location
9.6/10
Staff
9.8/10
Value for money
9.7/10
Guest reviews
based on 24 reviews
9.7/10
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